The viral TikTok trend claims that using a few supplements can help ease anxiety.
Anxiety sufferers have tested the effects of magnesium and vitamin D3 to help control their symptoms, and many say it works.
As a “huge anxiety sufferer,” TikTok user Tyler Wesley (@tylerjohnwesley) revealed in a July 7 video that he takes 500 mg of magnesium and one dose of vitamin D daily.
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He claimed that this combination of supplements eliminated his anxiety.
The TikToker (not pictured) claims that taking magnesium and vitamin D supplements has stopped her anxiety attacks. (iStock)
“I have no worries anymore,” he said in the video. “Thirty years, anxiety all my life, I don’t have it anymore.”
Wesleys TikTok has received over two million likes, and other users have also claimed that this method worked for them.
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One TikToker, @lolbrenden, “stitched” or responded to Wesley with another video explaining how taking magnesium and D3 also changed his anxiety symptoms.
Brenden, who was prescribed Klonopin, said he took just 200 mg of magnesium glycinate along with D3 supplements for four days and noticed results.

Magnesium supplements are displayed in a CVS Pharmacy in New York on September 14, 2023. (Angelica Stabile/Fox News Digital)
“I feel like I took Klonopin,” he said in the video, which has nearly five million views.
“I feel good, I feel normal, I have no anxiety.”
The TikToker reported that she has not had any anxiety or panic attacks since taking the supplements. In another video, he claimed that his sleep had also improved.
“Why didn’t the doctor make me try this first?” He asked.
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Dr. Chris Palmer, an assistant professor of psychiatry at Harvard Medical School in Boston, says that may be because there isn’t enough high-quality data to warrant recommendations for doctors.
But the “more likely” reason is that prescription drugs are “much more powerful at reducing anxiety than magnesium and vitamin D3,” the doctor wrote in an email exchange with Fox News Digital.

TikTok hackers say taking magnesium and D3 supplements helps curb anxiety symptoms. Doctors weighed in on these claims. (iStock)
“So they are very likely to work in the initial use in most people, to the satisfaction of both patients and clinicians,” said the doctor, who is also the author of Brain Energy.
“Unfortunately, prescription anxiolytics (benzodiazepines) are also more likely to lead to tolerance and dependence, which can be a problem for some people.”
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But the doctor suggests that magnesium probably works in some people because it has been studied for a long time “for a variety of psychiatric and neurological conditions.”
Although Palmer shared that the research consists mostly of “small pilot studies of poor quality,” some reviews, such as a study from the University of Leeds published in 2017, suggest that magnesium may help fight anxiety.

Research shows that magnesium can help with anxiety symptoms, according to Dr. Chris Palmer, an assistant professor of psychiatry at Harvard Medical School. (iStock)
“Magnesium plays a role in many metabolic reactions in the body and brain,” he said.
“One hypothesis for anxiety disorders is that the brain’s anxiety pathways/circuits are hyperstimulated, meaning they fire inappropriately and cause anxiety.”
“You don’t want to ingest things unless you know what the alternatives are, because even some natural things can be toxic to your body if taken in large amounts or the wrong way.”
“Magnesium is known to reduce the hyperexcitability of neurons and muscles, which is one reason it is commonly included in over-the-counter muscle relaxants,” the doctor continued.
“This mechanism may explain its ability to reduce anxiety in some people.”
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As for vitamin D, Palmer suggests that people with low levels may be more susceptible to anxiety or depression.
“Vitamin D plays many roles in the brain and body, but one of them is reducing oxidative stress, which is associated with depression and anxiety,” he said.

Palmer suggests that people with low levels of vitamin D may be more prone to anxiety or depression. (iStock)
“Therefore, correcting vitamin D deficiency in some people may play a role in treating anxiety.”
A randomized controlled trial of a combination of vitamin D3 and magnesium plus a placebo in children with ADHD, published in 2020 by the International Journal of Preventive Medicine, found that the magnesium/D3 duo improved anxiety symptoms and social problems, Palmer. noted.
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Psychologist Mary Karapetian Alvord, Ph.D., of Maryland, is more skeptical of the viral “hack.”
“I think we have to be careful when it’s just a few people posting testimonials,” Alvord said.
“You don’t want to ingest things unless you know what the alternatives are, because even some natural things can be toxic to your body if taken in large amounts or in the wrong way,” the doctor said.

Mary Karapetyan Alvord, Ph.D., is a psychologist and director of Alvord, Baker & Associates, LLC. (Mary Karapetyan Alvord, Ph.D.)
Just because “somebody says it doesn’t mean it’s the truth,” he also said.
As an alternative, Alvord suggested behavioral therapies such as interoceptive exposure and cognitive behavioral therapy.
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“The opposite of avoiding is doing something,” he said.
“Facing your fear helps you overcome it. If you don’t face it, the fear gets worse and worse because you’re building it up in your head.”
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